Nephroprotective Of Herbal Medicine And Its Prevention: A Review
Abstract
Drug-induced nephrotoxicity is one of the most common cause’s acute kidney injury. There are several nephrotoxic agents by various pathogenic mechanisms. Aminoglycoside antibiotics, chemotherapy agents, radiocontrast agents, and NSAIDs are common nephrotoxic substances. In recent years, natural compounds have appeared is increasingly used in the treatment of kidney diseases. Given too many available reports on the healing effects of various drugs plants against drug-related nephrotoxicity, we try to review protective effect of medicinal plants against certain kidney toxicity medicines.
Keywords:
Drug-induced nephrotoxicity, Aminoglycoside, nephrotoxic antibiotics Assessment
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References
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chronic carbon tetrachloride intoxication. Annu Res Rev Biol 2015(2):109–123. DOI: 10.9734/ ARRB/2015/8838.
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26. Chakrabortty S, Choudhary R. Hemidesmus indicus (Anantmool): rare herb of Chhattisgarh. Indian J Sci Res 2014;4(1):89–93.
27. Iftikhar A, Hasan IJ, Sarfraz M, et al. Nephroprotective effect of the leaves of Aloe barbadensis (Aloe vera) against toxicity induced bydiclofenac sodium in albino rabbits. West Indian Med J 2015;64(5):462.
28. Singh, A., Gowtham, S., Chakrapani, L.N., Ashokkumar, S., Kumar, S.K., Prema, V., Bhavani, R.D., Mohan, T. and Sathyamoorthy, Y.K., 2018. Aegeline vs Statin in the treatment of Hypercholesterolemia: A comprehensive study in rat model of liver steatosis. Functional Foods in Health and Disease, 8(1), pp.1-16.
29. Kpemissi M, Eklu-Gadegbeku K, Veerapur VP, et al. Antioxidant and nephroprotection activities of Combretum micranthum: a phytochemical, in-vitro and ex-vivo studies. Heliyon 2019;5(3):1365. DOI: 10.1016/j.heliyon.2019.e01365.
30. Shiv Chandra Singh, A., Yu, A., Chang, B., Li, H., Rosenzweig, A. and Roh, J.D., 2021. Exercise Training Attenuates Activin Type II Receptor Signaling in the Aged Heart. Circulation, 144(Suppl_1), pp.A14259-A14259.
31. Saha S, Verma RJ. Antinephrolithiatic and antioxidative efficacy of Dolichos biflorus seeds in a lithiasic rat model. Pharma Biol 2015;53(1):16–30. DOI: 10.3109/13880209.2014.909501.
32. Abdel-Hady H, El-Sayed MM, Abdel-Hady AA, et al. Nephroprotective activity of methanolic extract of Lantana camara and squash (Cucurbita pepo) on cisplatin-induced nephrotoxicity in rats and identification of certain chemical constituents of Lantana camaraby HPLC-ESI-MS. Pharmacognosy Journal 2018;10(1):136–147. DOI: 10.5530/pj.2018.1.24.
33. Shahbazi F, Dashti-Khavidaki S, Khalili H, Lessan-Pezeshki M. Potential Renoprotective Effects of Silymarin Against
Nephrotoxic Drugs: A Review of Literature. J Pharm Pharmaceut Sci. 2012;15:112-23.
34. Singh, A., 2022. Role of microbial metabolites in cardiovascular and human health. In Microbiome,
35. Immunity, Digestive Health and Nutrition (pp. 137-148). Academic Press.
36. Singh, A., 2022. Hyperlipidemia in cardiovascular health and digestion. In Nutrition and Functional Foods in Boosting Digestion, Metabolism and Immune Health (pp. 141-150). Academic Press.
37. Hadjzadeh MR, Keshavarzi Z, Tabatabaee Yazdi A, Ghasem Shirazi M, Rajaei Z, Khajavi Rad A. Effect of Alcoholic Extract of Nigella Sativa on Cisplatin-induced Toxicity in Rat. Iran J Kidney Dis. 2012;6:99-104.
38. Antunes LMG, Darin JDAC, Maria de Lourdes PB. Effects of the antioxidants curcumin or selenium on cisplatininduced nephrotoxicity and lipid peroxidation in rats. Pharmacol Res. 2001;43:145-50.
2. Schetz M, Dasta J, Goldstein S, Golper T. Drug-induced acute kidney injury. Curr Opin Crit Care. 2005;11:555-65.
3. Dhodi DK, Bhagat SB, Pathak D, Patel SB. Drug-induced nephrotoxicity. Int J Basic Clin Pharmacol. 2014;3:591-7.
4. Harirforoosh S, Jamali F. Renal adverse effects of nonsteroidal anti-inflammatory drugs. Expert Opin Drug Saf. 2009;8:669-81.
5. Perazella M. Drug-induced nephropathy: an update. Expert Opin Drug Saf. 2005;4:689-706.
6. Hosseinian S, Khajavi Rad A, Hadjzadeh MR, Mohamadian Roshan N, Havakhah S, Shafiee S. The protective effect of
Nigella sativa against cisplatin-induced nephrotoxicity in rats. Avicenna J Phytomed. 2016;6:44-54.
7. Khajavi Rad A, Ghazi L, Boroushaki MT, et al. Effect of commercial (vimang) and hydroalcoholic extract of Mangifera indica (Mango) on gentamicin-induced nephrotoxicity in rat. Avicenna J Phytomed. 2011;1:98-105.
8. Khorsandi L, Orazizadeh M. Protective effect of Curcuma longa extract on acetaminophen induced nephrotoxicity in mice. Daru. 2008;16:155-9.
9. Mohammad AA. Therapeutics role of Azadirachta indica (neem) and their active constituents in diseases prevention and treatment. J Evid Based Compl Altern Med 2016. 1–11.
Annie S, Rajagopal PL, Malini S. Effect of Cassia auriculata root extract on cisplatin and gentamicin-induced renal injury. Phytoemdicine 2005;12(8):550–560. DOI: 10.1016/j.phymed.2003.11.010.
10. Indhumathi T, Shilpa K, Mohandass S. Evaluation of nephroprotective role of Boerhaavia diffusa leaves against mercuric chloride induced toxicity in experimental rats. J Pharm Res 2011;4(6):1848–1850.
11. Singh, A., Srinivasan, A.K., Chakrapani, L.N. and Kalaiselvi, P., 2019. LOX-1, the common therapeutic target in hypercholesterolemia: a new perspective of antiatherosclerotic action of aegeline. Oxidative medicine and cellular longevity, 2019.
12. Devi MARL, Deepika MY, Nagaraju B, et al. Evaluation of nephroprotective activity of ethanolic extracts of Annona reticulatein gentamicin and cisplatin induced nephrotoxicity in rats. Int J PharmSci Res 2016;8(9):995.
13. Chandavarkar S, Desai SM, Gautam G. Nephroprotective activity of different extracts of Biophytum sensitivum (Linn.) DC. Int J Herb Med 2017;5(1):31–34.
14. Zaman R, Alam A, Jafri MA, et al. Nephroprotective effect of Beekh Kasni (roots of Cichorium intybus) in the form of methanolic and aqueous extract in gentamycin induced rat models. J Pharmacogn Phytochem 2017;6(3):337–341.
15. Roh, J., Hill, J.A., Singh, A.,Valero-Muñoz, M. and Sam, F., 2022. Heart failure with preserved ejection fraction: heterogeneous syndrome, diverse preclinical models. Circulation Research, 130(12), pp.1906-1925.
16. Shaheen U, Manzoor Z, Khaliq T, et al. Evaluation of nephroprotective effects of Foeniculum vulgare Mill, Solanum nigrum Linn. and their mixture against gentamicin- induced nephrotoxicity in albino rats. Int J Pharm Sci Rev Res 2014;25(1):1–9.
17. Abdel-Hady H, El-Sayed MM, Abdel-Hady AA, et al. Nephroprotective activity of methanolic extract of Lantana camara and squash (Cucurbita pepo) on cisplatin-induced nephrotoxicity in rats and identification of certain chemical constituents of Lantana camara by HPLC-ESI-MS. Pharmacognosy Journal 2018;10(1):136–147. DOI:
18. 10.5530/pj.2018.1.24.
19. Singh, A., Kumar, A. and Kalaiselvi, P., 2018. Aegeline, targets LOX1, the receptor for oxidized LDL to mitigate hypercholesterolemia: a new perspective in its anti-atherosclerotic action. Free Radical Biology and Medicine, 128, p.S41.
20. Abbas K, Rizwani GH, Zahid H, et al. Evaluation of nephroprotective activity of Musa paradisiaca L. in
gentamicin-induced nephrotoxicity. Pak J Pharm Sci 2017;30(3):881 890
21. Aiswarya N, Chandran V, TeerthanathS, et al. Nephroprotective effect of aqueous extract of Pimpinella anisum in gentamicin induced nephrotoxicity in Wistar rats. Pharmacogn J 2018;10(3):403–407. DOI: 10.5530/pj.2018.3.66.
22. Boini, K.M., singh, A. and Koka, S.S., 2021. Gut Microbial Metabolite Trimethylamine N-oxide Enhances Endoplasmic Reticular Stress and Promotes Endothelial Dysfunction. Circulation, 144(Suppl_1), pp.A14071-A14071.
23. Liman ML, Sunday EA. Hepatoprotective and nephroprotective effects of methanolic extract of different parts of Tamarindusindica Linn in rats following acute and
chronic carbon tetrachloride intoxication. Annu Res Rev Biol 2015(2):109–123. DOI: 10.9734/ ARRB/2015/8838.
24. Zaman R, Alam A, Choudhry SS, et al. Nephroprotective agents used in Unani medicine-an evidence based approach. J Nephrol Therapeut 2017(03):15–16. DOI: 10.4172/2161-0959.1000296.
25. Murali VP, Kuttan G. Curculigo orchioides Gaertn effectively ameliorates the uro- and nephrotoxicities induced by cyclophosphamide administration in experimental animals. Integr Cancer Ther 2016;15(2):205–215. DOI: 10.1177/1534735415607319.
26. Chakrabortty S, Choudhary R. Hemidesmus indicus (Anantmool): rare herb of Chhattisgarh. Indian J Sci Res 2014;4(1):89–93.
27. Iftikhar A, Hasan IJ, Sarfraz M, et al. Nephroprotective effect of the leaves of Aloe barbadensis (Aloe vera) against toxicity induced bydiclofenac sodium in albino rabbits. West Indian Med J 2015;64(5):462.
28. Singh, A., Gowtham, S., Chakrapani, L.N., Ashokkumar, S., Kumar, S.K., Prema, V., Bhavani, R.D., Mohan, T. and Sathyamoorthy, Y.K., 2018. Aegeline vs Statin in the treatment of Hypercholesterolemia: A comprehensive study in rat model of liver steatosis. Functional Foods in Health and Disease, 8(1), pp.1-16.
29. Kpemissi M, Eklu-Gadegbeku K, Veerapur VP, et al. Antioxidant and nephroprotection activities of Combretum micranthum: a phytochemical, in-vitro and ex-vivo studies. Heliyon 2019;5(3):1365. DOI: 10.1016/j.heliyon.2019.e01365.
30. Shiv Chandra Singh, A., Yu, A., Chang, B., Li, H., Rosenzweig, A. and Roh, J.D., 2021. Exercise Training Attenuates Activin Type II Receptor Signaling in the Aged Heart. Circulation, 144(Suppl_1), pp.A14259-A14259.
31. Saha S, Verma RJ. Antinephrolithiatic and antioxidative efficacy of Dolichos biflorus seeds in a lithiasic rat model. Pharma Biol 2015;53(1):16–30. DOI: 10.3109/13880209.2014.909501.
32. Abdel-Hady H, El-Sayed MM, Abdel-Hady AA, et al. Nephroprotective activity of methanolic extract of Lantana camara and squash (Cucurbita pepo) on cisplatin-induced nephrotoxicity in rats and identification of certain chemical constituents of Lantana camaraby HPLC-ESI-MS. Pharmacognosy Journal 2018;10(1):136–147. DOI: 10.5530/pj.2018.1.24.
33. Shahbazi F, Dashti-Khavidaki S, Khalili H, Lessan-Pezeshki M. Potential Renoprotective Effects of Silymarin Against
Nephrotoxic Drugs: A Review of Literature. J Pharm Pharmaceut Sci. 2012;15:112-23.
34. Singh, A., 2022. Role of microbial metabolites in cardiovascular and human health. In Microbiome,
35. Immunity, Digestive Health and Nutrition (pp. 137-148). Academic Press.
36. Singh, A., 2022. Hyperlipidemia in cardiovascular health and digestion. In Nutrition and Functional Foods in Boosting Digestion, Metabolism and Immune Health (pp. 141-150). Academic Press.
37. Hadjzadeh MR, Keshavarzi Z, Tabatabaee Yazdi A, Ghasem Shirazi M, Rajaei Z, Khajavi Rad A. Effect of Alcoholic Extract of Nigella Sativa on Cisplatin-induced Toxicity in Rat. Iran J Kidney Dis. 2012;6:99-104.
38. Antunes LMG, Darin JDAC, Maria de Lourdes PB. Effects of the antioxidants curcumin or selenium on cisplatininduced nephrotoxicity and lipid peroxidation in rats. Pharmacol Res. 2001;43:145-50.
Published
14/08/2023
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Malli, R., M, R. K., Mittal, S., GS, M., talukdar, A. J., Md, F., & Shree, S. (2023). Nephroprotective Of Herbal Medicine And Its Prevention: A Review. Journal of Innovations in Applied Pharmaceutical Science (JIAPS), 8(2), 33-38. Retrieved from https://www.saapjournals.org/index.php/jiaps/article/view/472
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