Anthelmintic activity of the flowers of Sesbania grandiflora Pers.
Abstract
In present study acetone, ethanol and aqueous extracts of the flowers of Sesbania grandiflora were investigated for their anthelmintic activity against Pheretima posthuma. Three concentrations (100, 150, 200 mg/ml) of each extract were studied. This study is mainly concerned with the determination of time of paralysis and time of death of the worms. When there was a gradual increase in the dose, a gradual increase in the anthelmintic activity was observed. The ethanolic extract of the flower showed a significant anthelmintic activity at highest concentration of 200 mg/ml.
Keywords:
Anthelmintic activity, Sesbania grandiflora, Pheretima posthuma
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References
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3. S.Nesamony: Medicinal plants, State Institute of Languages, Kerala, First edition 2001:1-3.
4. Kokate CK :Practical Pharmacognosy, Vallabha Prakashan, New Delhi, Fourth edition 1999:149-156.
5. Khandelwal KR: Practical Pharmacognosy Technique and Experiments, Nirali Prakashan, Pune, Second edition 2000: 149-156
6. Ajaiyeoba EO, Onocha PA, Olarenwaju OT. In-vitro anthelmintic properties of Buchholziacoiaceae and Gynandropsisgynandra extract. Pharm. Biol. 2001; 39(3): 217-20.
7. Vigar Z:Atlas of Medical Parasitology. Singapore: P.G. Publishing House, Second edition 1984.
8. Thorn GW, Adams RD, Braunwald E, Isselbacher KJ, Petersdorf RG. Harrison's Principles of Internal Medicine. New York:McGraw Hill Co; 1977
9. Sollmann, T. Anthelmintics: Their efficiency as tested on earthworms. J Pharmacol. Exp. Ther 1918; 12(1s):29-70
10. Szewezuk, V.D., Mongelli, E.R and Pomillio, A.b. Ant parasitic activity of Meliaazardirachgowing in Argentina. Molecular Med Chem 2003; 1:54-7.
11. Shivkumar YM, Kumar VL. Anthelmintic activity of latex of Calotropisprocera. Pharm. Bio. 2003; 41:263-265.
12. Piyush Jain et.al, Anthelmintic potential of herbal drugs. Int. J. Res. Dev. L. Sci 2013; 2(3):412-417.
13. Barba H.R et.al. Anthelmintic comparative study of Solanumlycocarpum St. Hill extracts in mice naturally infected with Aspiculuris tetraptera. Nature and Science 2010; 8(4):94-100.
14. Chandrasekhar C.H et.al. Anthelmintic activity of the crude extract of Ficusrecemosa. International journal of Green Pharmacy 2008; 100-103.
15. Jain D et.al. Anthelmintic drugs. Journal of advances in drug research 2011; 1(2):965-967.
16. Scalbert A. Antimicrobial properties of tannins. Phytochem 1991; 30:3875-3883.
17. Roy H et al. Preliminary phytochemical investigation and anthelmintic activity of Acanthospermumhispidum. Journal of Pharmaceutical Science and Technology. 2010; 2(5):217-221.
Published
30/06/2016
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P.L. Rajagopal, K, P., & K. R. Sreejith. (2016). Anthelmintic activity of the flowers of Sesbania grandiflora Pers. Journal of Innovations in Applied Pharmaceutical Science (JIAPS), 1(2), 8-11. Retrieved from https://www.saapjournals.org/index.php/jiaps/article/view/173
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