A case report on phyllodes breast tumor

  • Ch.Sowjanya Student, Pharm.D, Avanthi Institute of Pharmaceutical Sciences, AIPS.
  • G.V.S.Pranathi Student, Pharm.D, Avanthi Institute of Pharmaceutical Sciences, AIPS.
  • B.Pallavi Associate Professor, Department of Pharmacy Practice, AIPS.
  • V.Lohitha Associate Professor, Department of Pharmacy Practice, AIPS.
  • V.C.Randeep Raj Associate Professor, Department of Pharmacy Practice, AIPS.

Abstract

Phyllodes tumors of the breast are relatively rare fibroepithelial neoplasms that present along a morphologic spectrum, ranging from benign to malignant. These tumors are biphasic, comprising both epithelial and stromal components, and account for less than 1% of all breast tumors. While most phyllodes tumors are benign, a small proportion can recur locally, and very rarely, they metastasize. The tumors are classified into three categories: benign, borderline, and malignant phyllodes tumors. The overall prognosis is favorable, with a 10-year survival rate of 87%. The risk of recurrence is influenced by tumor size and the surgical method used. The median size of phyllodes tumors is approximately 4 cm, though they can grow larger, sometimes presenting with dilated veins and a bluish discoloration of the overlying skin. Palpable axillary lymphadenopathy is observed in 10-15% of patients, but less than 1% has pathologically positive lymph nodes.

Keywords: Phyllodes tumors, malignant phyllodes tumors, axillary lymphadenopathy

References

1. Hasdemir S, Tolunay Ş, Özşen M, Gökgöz MŞ. Phyllodes tumor of the breast: a clinicopathological evaluation of 55 cases. European Journal of Breast Health. 2020 Jan;16(1):32.
2. Damaskos C, Garmpis N, Kyriakopoulou A, Nikolettos K, Garmpi A, Dimitroulis D, Tsikouras P, Nikolettos N, Effraimidou EI, Vrettou K, Psilopatis I. Rapid-Growing Phyllodes Tumor after an Accidental Bump on the Breast: A Case Report. Case Reports in Oncology. 2024 Jun 18;17(1):935-41.
3. Mishra SP, Tiwary SK, Mishra M, Khanna AK. [Retracted] Phyllodes Tumor of Breast: A Review Article. International Scholarly Research Notices. 2013;2013(1):361469.
4. Esperança-Martins M, Melo-Alvim C, Dâmaso S, Lopes-Brás R, Peniche T, Nogueira-Costa G, Abreu C, Luna Pais H, de Sousa RT, Torres S, Gallego-Paez LM. Breast Sarcomas, Phyllodes Tumors, and Desmoid Tumors: Turning the Magnifying Glass on Rare and Aggressive Entities. Cancers. 2023 Aug 2;15(15):3933.
5. Lissidini G, Mulè A, Santoro A, Papa G, Nicosia L, Cassano E, Ashoor AA, Veronesi P, Pantanowitz L, Hornick JL, Rossi ED. Malignant phyllodes tumor of the breast: a systematic review. Pathologica. 2022 Apr;114(2):111.
Published
06/10/2024
Statistics
176 Views | 32 Downloads
Citatons
How to Cite
Ch, S., G.V.S, P., B, P., V, L., & V, C. R. (2024). A case report on phyllodes breast tumor. Journal of Case Studies and Case Reports, 3(3), 1-3. https://doi.org/10.37022/jcscr.v3i3.629
Section
Case Reports