A REVIEW ON ADVANCED WOUND CARE PRODUCTS AND THEIR CLINICAL APPLICATIONS
Abstract
Because of inadequate biological signalling, the intricate organic process of wound healing is frequently slowed down in chronic and non-healing wounds. Traditional mechanical running is proposed by outdated remedies like coil bandages and covering inserts, but they lack the bioactive components needed for well-organized tissue regeneration. Due to recent advancements in reformative medicine, secretum-loaded biomaterials have emerged as a useful adjunct to conventional wound care methods. Cells such as mesenchymal stem cells create the secretum, which contains bioactive chemicals such as growth effects, cytokines, and extracellular vesicles. These particles are essential for skin growth and renewal as well as for controlling inflammation.
Keywords:
covering tissues, acute besides chronic wounds, and helical healing
Downloads
Download data is not yet available.
References
1. Pan H, Fan D, Cao W, Zhu C, Duan Z. Preparation and characterization of breathable haemostatic hydrogel dressings and determination of their effects on full-thickness defects. Polymers (Basel). 2017;9(12):727.
2. Finnegan S, Percival SL. Clinical and antibiofilm efficacy of antimicrobial hydrogels. Adv Wound Care (New Rochelle). 2015;4(7):398-406.
3. Hwisa NT, Gindi S, Rao CB, Katakam P, Chandu BR. Evaluation of antiulcer activity of Picrasma quassioides Bennett aqueous extract in rodents. Vedic Res Int Phytomedicine. 2013;1:27.
4. Kiranmai M, Renuka P, Brahmaiah B, Chandu BR. Vitamin D as a promising anticancer agent. Int J Res Pharm Chem. 2012;2(2):636-649.
5. Sreekanth N, Awen BZ, Rao CB. Development and validation of new analytical methods for the estimation of capecitabine in pharmaceutical dosage form. Res J Pharm Biol Chem Sci. 2012;1(2):39-46.
6. Schmeck HE, Sileshi B, Jamiolkowski RM, Albala DM, Shapiro ML, Lawson JH. A comprehensive review of topical haemostatic agents: Efficacy and recommendations for surgical practice. Ann Surg. 2010;251(2):217-228.
7. Nama S, Chandu BR, Awen BZ, Khagga M. Development and validation of a new RP-HPLC method for the determination of aprepitant in bulk and pharmaceutical dosage forms. Trop J Pharm Res. 2011;10(4):489-495.
8. Vijayalakshmi P, Girish C, Mendham R, Rao CB, Nama S. A review on Alzheimer’s disease. Int J Pharma Biosci. 2014;4(2):19-27.
9. Johnson TP, Thompson MJ. Collagen's role in chronic wound healing. Wound Healing Sci Rev. 2019;14(3):45-53.
10. Rani TT, Brahmaiah B, Revathi B, Nama S, Chandu B. Targeting of anti-cancer drugs through nanoparticles. Int J Pharm Ther. 2013;4(3):154-159.
11. Zhang M, Wang G, Wang D, et al. Ag@MOF-loaded chitosan nanoparticle and polyvinyl alcohol/sodium alginate/chitosan bilayer dressing for wound healing applications. Int J Biol Macromol. 2021;175:481-494.
12. Wan R, Weissman JP, Grundman K, Lang L, Grybowski DJ, Galiano RD. Diabetic wound healing: The impact of diabetes on myofibroblast activity and its potential therapeutic treatments. Wound Repair Regen. 2021;29(4):573-581.
13. Moini A, Pedram P, Makvandi P, Malinconico M, d'Ayala GG. Wound healing and antimicrobial effect of active secondary metabolites in chitosan-based wound dressings: A review. Carbohydr Polym. 2020;233:115839.
14. Suarato G, Bertorelli R, Athanassiou A. Borrowing from nature: Biopolymers and biocomposites as smart wound care materials. Front Bioeng Biotechnol. 2018;6:137.
15. Barrientos S, Stojadinovic O, Golinko MS, Brem H, Tomic-Canic M. Growth factors and cytokines in wound healing. Wound Repair Regen. 2008;16(5):585-601.
16. Frykberg RG, et al. Chronic wounds: Management and treatment strategies. Adv Wound Care (New Rochelle). 2015;4(9):560-582.
17. Organogenesis Inc. Puraply Antimicrobial [package insert]. Canton (MA): Organogenesis Inc.; 2020.
18. McCarty SM, et al. The role of antimicrobial dressings in wound management. Adv Wound Care (New Rochelle). 2013;2(8):438-447.
19. Wright JB, Lam K, Burrell RE. Wound management in an era of increasing bacterial antibiotic resistance: A role for topical silver treatment. Am J Infect Control. 1998;26(6):572-577.
20. O’Callaghan S, Galvin P, O’Mahony C, Moore Z, Derwin R. “Smart” wound dressings for advanced wound care: A review. J Wound Care. 2020;29(7):394-406.
2. Finnegan S, Percival SL. Clinical and antibiofilm efficacy of antimicrobial hydrogels. Adv Wound Care (New Rochelle). 2015;4(7):398-406.
3. Hwisa NT, Gindi S, Rao CB, Katakam P, Chandu BR. Evaluation of antiulcer activity of Picrasma quassioides Bennett aqueous extract in rodents. Vedic Res Int Phytomedicine. 2013;1:27.
4. Kiranmai M, Renuka P, Brahmaiah B, Chandu BR. Vitamin D as a promising anticancer agent. Int J Res Pharm Chem. 2012;2(2):636-649.
5. Sreekanth N, Awen BZ, Rao CB. Development and validation of new analytical methods for the estimation of capecitabine in pharmaceutical dosage form. Res J Pharm Biol Chem Sci. 2012;1(2):39-46.
6. Schmeck HE, Sileshi B, Jamiolkowski RM, Albala DM, Shapiro ML, Lawson JH. A comprehensive review of topical haemostatic agents: Efficacy and recommendations for surgical practice. Ann Surg. 2010;251(2):217-228.
7. Nama S, Chandu BR, Awen BZ, Khagga M. Development and validation of a new RP-HPLC method for the determination of aprepitant in bulk and pharmaceutical dosage forms. Trop J Pharm Res. 2011;10(4):489-495.
8. Vijayalakshmi P, Girish C, Mendham R, Rao CB, Nama S. A review on Alzheimer’s disease. Int J Pharma Biosci. 2014;4(2):19-27.
9. Johnson TP, Thompson MJ. Collagen's role in chronic wound healing. Wound Healing Sci Rev. 2019;14(3):45-53.
10. Rani TT, Brahmaiah B, Revathi B, Nama S, Chandu B. Targeting of anti-cancer drugs through nanoparticles. Int J Pharm Ther. 2013;4(3):154-159.
11. Zhang M, Wang G, Wang D, et al. Ag@MOF-loaded chitosan nanoparticle and polyvinyl alcohol/sodium alginate/chitosan bilayer dressing for wound healing applications. Int J Biol Macromol. 2021;175:481-494.
12. Wan R, Weissman JP, Grundman K, Lang L, Grybowski DJ, Galiano RD. Diabetic wound healing: The impact of diabetes on myofibroblast activity and its potential therapeutic treatments. Wound Repair Regen. 2021;29(4):573-581.
13. Moini A, Pedram P, Makvandi P, Malinconico M, d'Ayala GG. Wound healing and antimicrobial effect of active secondary metabolites in chitosan-based wound dressings: A review. Carbohydr Polym. 2020;233:115839.
14. Suarato G, Bertorelli R, Athanassiou A. Borrowing from nature: Biopolymers and biocomposites as smart wound care materials. Front Bioeng Biotechnol. 2018;6:137.
15. Barrientos S, Stojadinovic O, Golinko MS, Brem H, Tomic-Canic M. Growth factors and cytokines in wound healing. Wound Repair Regen. 2008;16(5):585-601.
16. Frykberg RG, et al. Chronic wounds: Management and treatment strategies. Adv Wound Care (New Rochelle). 2015;4(9):560-582.
17. Organogenesis Inc. Puraply Antimicrobial [package insert]. Canton (MA): Organogenesis Inc.; 2020.
18. McCarty SM, et al. The role of antimicrobial dressings in wound management. Adv Wound Care (New Rochelle). 2013;2(8):438-447.
19. Wright JB, Lam K, Burrell RE. Wound management in an era of increasing bacterial antibiotic resistance: A role for topical silver treatment. Am J Infect Control. 1998;26(6):572-577.
20. O’Callaghan S, Galvin P, O’Mahony C, Moore Z, Derwin R. “Smart” wound dressings for advanced wound care: A review. J Wound Care. 2020;29(7):394-406.
Published
20/06/2026
Statistics
13 Views | 18 Downloads
Citatons
How to Cite
Thumati, M. “A REVIEW ON ADVANCED WOUND CARE PRODUCTS AND THEIR CLINICAL APPLICATIONS”. International Journal of Health Care and Biological Sciences, Vol. 7, no. 3, June 2026, pp. 20-24, https://www.saapjournals.org/index.php/ijhcbs/article/view/906.
Issue
Section
Review Articles
.