MICRO ENCAPSULATION: FROM CONCEPT TO COMMERCIAL APPLICTIONS

  • S. Navami Priyadarshini Institute of Pharmaceutical Education and Research, 5TH Mile, Pulladigunta, Guntur-522017, Andhra Pradesh, India.

Abstract

This review article delves into the dynamic realm of microencapsulation, a technology that encapsulates active ingredients within microscopic particles. The membrane dissolves itself when stimulated, releasing the core at the desired time or place. Microencapsulation has many applications in the food, agricultural, pharmaceutical, and medical industries. It has been used in flavours, acids, oils, vitamins, and microorganisms. This article comprehensively explores various microencapsulation techniques, ranging from traditional methods to state-of-the-art technologies. Microencapsulation offers the crucial functionality of controlling the release of food ingredients at precise locations and timings, ensuring optimal effectiveness. It examines the applications of microencapsulation in different industries including pharmaceutical, agriculture, food, printing, cosmetic, textile and defence. Also highlighting its impact on product stability, controlled release and enhanced performance in different areas of science and technology. In the realm of pharmaceuticals and various other industries, microencapsulation plays a crucial role in enhancing stability, protecting sensitive substances and regulating the release of active ingredients. Microencapsulation is garnering significant attention across various domains including commercial development and research.

Keywords: Microencapsulation technology, microcapsule, polymers, pharmaceuticals, techniques, Centrifugal extrusion, Polymerization, Coacervation

Downloads

Download data is not yet available.

References

1. Fanger GO. Microencapsulation: A brief history and introduction. In: Microencapsulation: Processes and Applications. 1974. p.1-20.
2. Frascareli EC, Silva VM, Tonon RV, Hubinger MD. Effect of process conditions on the microencapsulation of coffee oil by spray drying. Food Bioprod Process. 2012;90(3):413-424.
3. Lensen D, Vriezema DM, van Hest JCM. Polymeric microcapsules for synthetic applications. Macromol Biosci. 2008;8(11):991-1005.
4. Madene A, Jacquot M, Scher J, Desobry S. Flavour encapsulation and controlled release—A review. Int J Food Sci Technol. 2006;41(1):1-21.
5. Maalouf GE. Microcapsules useful in carbonless copying systems and process for their preparation. US Patent 4,000,087. Washington (DC): US Patent and Trademark Office; 1976.
6. Jyothi SS, Seethadevi A, Prabha KS, Muthu Prasanna P, Pavitra P. Microencapsulation: A review. Int J Pharm Biol Sci. 2012;3(2):509-531.
7. Choudhury N, Meghwal M, Das K. Microencapsulation: An overview on concepts, methods, properties and applications in foods. Food Front. 2021;2(4):426-442.
8. Sarella PN, Vegi S, Vendi VK, Vipparthi AK, Valluri S. Exploring aquasomes: A promising frontier in nanotechnology based drug delivery. Asian J Pharm Res. 2024;14(2):153-161.
9. Tummala SR, Gorrepati N. AI-driven predictive analytics for drug stability studies. J Pharma Insights Res. 2024;2(2):188-198.
10. Buchi Raju R, Nama S, Sakala B, Chandu BR, Kommu A, Chebrolu JK, Yedulapurapu N. Vesicular drug delivery system: An overview. Res J Pharm Biol Chem Sci. Year not available.
11. Mogal RT, Patil MP. Microencapsulation as a tool for controlled drug delivery. In: Novel Drug Delivery Systems (Part 1). Bentham Science Publishers; 2024. p.128-168.
12. Mendake MR, Hatwar MP, Bakal RL, Kohale NB. Microencapsulation: A review. Int J Multidiscip Res. 2024;6(4):1-18.
13. Ganapati S, Ramalingam P, Babu Rao CH. SAR study: Impact of hydrazide hydrazones and sulphonamide side chain on in vitro antimicrobial activity of quinoxaline. Int J Pharmacol Biol. 2008;2(2):13-18.
14. Mishra DK, Jain AK, Jain PK. A review on various techniques of microencapsulation. Int J Pharm Chem Sci. 2013;2(2):962-968.
15. Poshadri A, Aparna K. Microencapsulation technology: A review. J Res ANGRAU. 2010;38(1):86-102.
16. Bakry AM, Abbas S, Ali B, Majeed H, Abouelwafa MY, Mousa A, Liang L. Microencapsulation of oils: A comprehensive review of benefits, techniques, and applications. Compr Rev Food Sci Food Saf. 2016;15(1):143-182.
17. Bansode SS, Banarjee SK, Gaikwad DD, Jadhav SL, Thorat RM. Microencapsulation: A review. Int J Pharm Sci Rev Res. 2010;1(2):38-43.
18. Amgoth KM, Tummala SR. LC-MS/MS approach for the quantification of five genotoxic nitroso impurities in varenicline. J Res Pharm. 2022;26(6):1685-1693.
19. Ghosh SK. Functional coatings and microencapsulation: A general perspective. In: Functional Coatings by Polymer Microencapsulation. 2006. p.1-28.
20. Amulya A, Sirisha V, Rao CB, Chennam JV. Current trends on role of nanoparticles on pulmonary diseases. Int J Res Pharm Chem. 2012;2(3):685-703.
21. Dey B, Katakam P, Mitra A, Chandu BR. Comparative evaluation of hypoglycaemic potentials of Eucalyptus spp. leaf extracts and their encapsulations for controlled delivery. J Pharm Drug Deliv Res. 2014;3(2).
22. Hwisa NT, Katakam P, Chandu BR, Adiki SK. Solvent evaporation techniques as promising advancement in microencapsulation. Vedic Res Int Biol Med Chem. 2013;1:8-22.
23. Katakam P, Diaf SR, Dey B, Adiki SK, Chandu BR, Chowdary KP. A comparative evaluation of drug release and permeability of ethyl cellulose, cellulose acetate and Eudragit RS100 microspheres. Int J Sci Res Knowl. 2014;2(2):75-82.
Published
20/06/2026
Statistics
15 Views | 22 Downloads
Citatons
How to Cite
S, N. “MICRO ENCAPSULATION: FROM CONCEPT TO COMMERCIAL APPLICTIONS ”. International Journal of Health Care and Biological Sciences, Vol. 7, no. 3, June 2026, pp. 6-10, https://www.saapjournals.org/index.php/ijhcbs/article/view/903.
Section
Review Articles