Analgesic activity of the aqueous extract of Dioscorea hispida Dennst (Kurot) rhizome

Reynalyn G. Lee Reynalyn G. Lee; Karina Milagros R. Cui-Lim Karina Milagros R. Cui-Lim

Reynalyn G. Lee Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department of Physical Sciences, College Science, University Eastern Philippines, Catarman N. Samar, 6400 Philippines Department
Karina Milagros R. Cui-Lim University Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 Philippines University Research Office, of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 Philippines University Research Office, of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 Philippines University Research Office, of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 Philippines University Research Office, of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 Philippines University Research Office, of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 Philippines University Research Office, of Eastern Philippines, Catarman N. Samar, 6400 Philippines University Research Office, of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 Philippines University Research Office, of Eastern Philippines, Catarman N. Samar, 6400 Philippines University Research Office, of Eastern Philippines, Catarman N. Samar, 6400 Philippines University Research Office, of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 Philippines University Research Office, of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 Philippines University Research Office, of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 Philippines University Research Office, of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 Philippines University Research Office, of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 Philippines University Research Office, of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 PhilippinesUniversity Research Office, University of Eastern Philippines, Catarman N. Samar, 6400 Philippines

Abstract

Objective: Dioscorea hispida Dennst is a wild yam that is locally known as ‘Kurot’ in Northern Samar, Philippines. The main objective of the study was to determine the analgesic activity of the kurot rhizome extract.

Methods: In this study, the rhizome of the plant extract was collected from Lavezares Northern Samar. An aqueous rhizome extract of the plant was prepared for analysis. The phytochemical characteristics like alkaloids, steroids and anthraquinones and the analgesic activity using acetic acid-induced writhing of the rhizome extract of kurot was determined.

Results: Results of the phytochemical screening and the analgesic activity showed that the rhizome extract of kurot may exhibit potential application in variety of analgesic products as shown in the decrease of the mean squirm of the experimental animals which is comparable to the commercially available drug.

Conclusion: In this work, it was concluded that the rhizome extract of kurot possesses analgesic activity.

Keywords: Analgesic activity, Kurot, Phytochemical screening, Acid-induced writhing

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References

1. Tewrakul S, Itharat, A. Anti-allergic substances from the rhizomes of Dioscorea membrenacea. Bioorg Med Chem
2006; 14, 8707-8711.
2. Wang S, Gao W, Liu H, Chen H, Yu J, Xiao P. Studies on the physicochemical, morphological, thermal and crystalline properties of starches separated from different Dioscorea opposita cultivars. Food Chem. 2006, 96, 591-596.
3. Nadiha MZ, Fazilah A. Comparative susceptabilities of sago, potato and corn starches to alkali treatment. Food Chem 2010; 1053-1059.
4. Cogne AL, Marston A, Mavi S, Hostettmann K. Study of two plants in traditional medicine in Zimbabwe for skin problems and rheumatism: Dioscorea sylvatica and Urginea altissima. J Ethnopharmacol 2011; 75, 51-53.
5. Wang T, Duan JA, Anti-inflammatory and analgesic activity of different extracts of Commiphora myrrha. J Ethnopharmacol 2011; 134, 251-258.
6. Guevara, Beatrice Q., A Guide Book to Plant Screening Phytochemical and Biological. Revised ed. Espana, Manila University of Santo Tomas Publishing House, 2005.