A review on niosomes as novel drug delivary system

Sireesha Badri; Sailaja P; Naga Rekha Annagowni; Raja Sekhar Lunjala; Bala Nagaraju B; Seshi Kumar Reddy B; Seshu D

doi:10.46956/ijihd.v7i5.352

Badri Sireesha Assistant professor, Sankar Reddy Institute of Pharmaceutical Sciences, Salakalaveedu(V), Bestavaripeta (M), Prakasam (D), Pincode-523370
P. Sailaja B.Pharmacy, Sankar Reddy Institute of Pharmaceutical Sciences, Salakalaveedu(V), Bestavaripeta (M), Prakasam (D), Pincode-523370
Annagowni Naga Rekha B. Pharmacy, Sankar Reddy Institute of Pharmaceutical Sciences, Salakalaveedu (V), Bestavaripeta (M), Prakasam (D), Pincode- 523370
Lunjala Raja Sekhar B. Pharmacy, Sankar Reddy Institute of Pharmaceutical Sciences, Salakalaveedu (V), Bestavaripeta (M), Prakasam (D), Pincode- 523370
B. Bala Nagaraju B. Pharmacy, Sankar Reddy Institute of Pharmaceutical Sciences, Salakalaveedu (V), Bestavaripeta (M), Prakasam (D), Pincode- 523370
B.Seshi Kumar Reddy B. Pharmacy, Sankar Reddy Institute of Pharmaceutical Sciences, Salakalaveedu (V), Bestavaripeta (M), Prakasam (D), Pincode- 523370
D. Seshu B. Pharmacy, Sankar Reddy Institute of Pharmaceutical Sciences, Salakalaveedu (V), Bestavaripeta (M), Prakasam (D), Pincode- 523370

DOI https://doi.org/10.46956/ijihd.v7i5.352

Abstract

Niosomes are a novel drug delivery system, in which the medication is encapsulated in a vesicle. Vesicle is composed of a bilayer of non-ionic surface active agents and hence the name niosomes. It can be used as carrier of amphiphilic and lipophilic drug. Niosomes are biodegradable, biocompatible nonimmunogenic and exhibit flexibility in their structural characterization. Niosomes have great drug delivery potential for targeted delivery of anti-cancer, anti-infective agents and various diseases. Technologies modify drug release profile, absorption, distribution and elimination for the benefit of: Improving product efficacy and safety, Patient convenience and compliance.

Keywords: Uni-lamellar, Multi-lamellar, Niosomes, compositions, bilayer, surfactant, drug entrapment

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