Anthelmintic potential of ethanolic extract of Lantana camara linn flowers

Akash Kumar Akash Kumar; Narendra Vyas Narendra Vyas; Sapna Malviya Sapna Malviya; Anil Kharia Anil Kharia

Akash Kumar Modern Institute of Pharmaceutical Sciences, Indore-453111 (India)
Narendra Vyas Modern Institute of Pharmaceutical Sciences, Indore-453111 (India)
Sapna Malviya Modern Institute of Pharmaceutical Sciences, Indore-453111 (India)
Anil Kharia Modern Institute of Pharmaceutical Sciences, Indore-453111 (India)

Abstract

Objective: The ethanolic extract the flowers of Lantana camara Linn were screened for anthelmintic activity using earthworms Pheretima posthuma. Methods: Various concentrations of plant extract were tested in the bioassay. Albendazole (20 mg/ml) was used as reference standard drug whereas distilled water as control. The parameters like the time of paralysis and the time of death were determined by using the ethanolic extract the flowers of L. camara at the concentrations of 250 and 500 mg/ml. Results: Extract exhibited significant anthelmintic activity at highest concentration of 500 mg/ml. The results of the study show that ethanolic extract of flowers of L. camara Linn possesses significant anthelmintic activity at a dose of 500 mg/ml when compared to standard drug albendazole at 20mg/ml concentration. Conclusion: Ethanolic extract of flowers of L. camara at a dose of 500 mg/ml possesses vermicidal activity and found to be effective as an anthelmintic.

Keywords: Anthelmintic activity, Lantana camara Linn, Pheretima posthuma, Ethanolic extract

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